Marianna Sadagurski
Division
Institute of Environmental Health Sciences
Department of Biological Sciences
Laboratory Web Site
Research
Our research program focuses on the hypothalamic regulation of metabolism in states of environmental stress, obesity, and aging. The hypothalamus integrates information from the liver, muscle, fat, and other organs, and orchestrates whole-body metabolic homeostasis. We study signaling pathways operating in hypothalamic neurons and glia cells (astrocytes and microglia), which are highly relevant to the control of systemic metabolism and the age-associated changes in the glia-neuron interactions.
Research Interests
Hypothalamic regulation of metabolism in health and disease; Pollution and hypothalamic inflammation; Anti-aging interventions and aging brain; Maternal environment, metabolic disease and aging
Disease/Disorder Research
Hypothalamic regulation of metabolism in states of environmental stress, obesity, and aging.