Marianna Sadagurski
Division
Institute of Environmental Health Sciences
Department of Biological Sciences
Laboratory Web Site
Research
Our research program focuses on the hypothalamic regulation of metabolism in states of environmental stress, obesity, and aging. The hypothalamus integrates information from the liver, muscle, fat, and other organs, and orchestrates whole-body metabolic homeostasis. We study signaling pathways operating in hypothalamic neurons and glia cells (astrocytes and microglia), which are highly relevant to the control of systemic metabolism and the age-associated changes in the glia-neuron interactions.
Research Interests
Hypothalamic regulation of metabolism in health and disease; Pollution and hypothalamic inflammation; Anti-aging interventions and aging brain; Maternal environment, metabolic disease and aging
Disease/Disorder Research
Hypothalamic regulation of metabolism in states of environmental stress, obesity, and aging.
Publications
Courses taught by Marianna Sadagurski
Fall Term 2025 (future)
Fall Term 2023
Recent university news spotlights
- Wayne State study links type 2 diabetes and air pollution
- Wayne State study links type 2 diabetes and air pollution
- Study links air pollution exposure to type 2 diabetes susceptibility
- Academic Recognition Ceremony celebrates faculty, staff excellence
- Wayne State receives funding to explore intergenerational impacts of benzene exposure
- Wayne State receives new grant to study effects of anti-diabetes drug