Anna Moszczynska
Office Address
Pharmaceutical Sciences Department
College of Pharmacy and Health Sciences
Wayne State University
259 Mack Avenue
Detroit, MI 48201
Division
Pharmaceutical Sciences
Education/Training
- 1988 M.Sc. in Chemical Engineering, Institute of Technical Biochemistry, with Honours,Technical University of Lodz, Poland
- 1995 M.Sc. in Cell Biology, Department of Anatomy and Cell Biology, University of Toronto, ON, Canada
- 2002 Ph.D. in Neurochemistry, Institute of Medical Science, University of Toronto, ON, Canada
- 2005 Post-doctoral Fellowship in Molecular Neurobiology, Center for Addiction and Mental Health, Toronto, ON, Canada
- 2007 Post-doctoral Fellowship in Molecular Genetics, University of Guelph, ON, Canada 2008 Postdoctoral Fellowship in Pharmacology, Boston University, Boston, MA, USA
Office Phone
313-577-1257
Research Interests
Research Interests include Addiction and Substance Abuse, Neuropharmacology, and Neurodegenerative Diseases.
My current research focuses on discovery of novel molecular and epigenetic drug targets to attenuate methamphetamine (METH) abuse in heavy users of the drug. My primary research interest is parkin and proteasome, two components of the ubiquitin-proteasome system, as drug targets in MUD. My secondary research interest lies in transposable elements (rat LINE-1 an Identifier element) and their role in mediating METH neurotoxicity.
Research Methods
Research Models: Rat model of heavy METH use, rat models of METH neurotoxicity (chronic METH and METH overdose), rat mode of parkin deficiency (Park2-/- rats) and parkin excess (parkin overexpressing rats).
Main Research Techniques: Native and 2D gel electrophoresis/western blotting, multi-PAGE electrophoresis/western blotting, co-immunoprecipitation, immunohistochemistry and confocal microscopy, in vivo gene transfer with adeno-associated viral vectors, manipulation of protein-protein interactions with TAT-peptides, anxiety and cognitive behavioral tests, and enzymatic assays, as well as proteomic analysis.
Publications
Courses taught by Anna Moszczynska
Fall Term 2025 (future)
Winter Term 2025
Fall Term 2024
Spring-Summer Term 2024
Winter Term 2024
Fall Term 2023
- PHA5135 - Pharmacotherapeutic Problem Solving II :Nephrology, Cardiology, Endocrinology, Gynecology, Urology
- PSC5992 - Directed Study in Pharmacology