Obesity and Diabetes
| Bruce Berkowitz, Ph.D. | Anatomy & Cell Biology, Ophthalmology |
| James Granneman, Ph.D. | Neurology, Center for Molecular Medicine and Genetics |
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| Bruce Berkowitz, Ph.D. Anatomy & Cell Biology, Ophthalmology | |
| Research Interest | Our goal is to prevent vision loss and blindness due to diabetic retinopathy and neurodegenerative disease. We develop and apply functional MRI methods to detect the effectiveness of a treatment earlier in the course of disease than is currently possible. | |
| Disease/Disorder | diabetic retinopathy, retinopathy of prematurity, age-related macular degeneration and retinitis pigmentosa | |
| Species | Human, rats and mice. | |
| Methods | Manganese-Enhanced MRI (MEMRI). | |
| Key Collaborators | Tim Kern (Case Western Reserve University), Paul Tofts (Brighton and Sussex Medical School, England) | |
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| James Granneman, Ph.D. Psychiatry & Behavioral Neurosciences, Pathology | |
| Research Interest | Adipose tissue remodeling, molecular mechanisms of lipolysis in fat and muscle, drug target discovery. | |
| Disease/Disorder | Diabetes and obesity. | |
| Species | Mice. | |
| Methods | Confocal microscopy, live cell protein-protein interaction assays, molecular biology, cell biology and high throughput compound screening | |
| Key Collaborators | HP Moore, Ryan Thummel, Mark Cheng, Guangzhao Mao | |
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