
Itzick Nahmoud
Predoctoral Candidate
Itzick Nahmoud
Biography
Awards and Honors
o 2017-2019: BP-ENDURE NIH Fellowship, Hunter College
o 2016-2019: Thomas Hunter Honors Program, Biochemistry, Hunter College
o 2016: Undergraduate Research Fellowship, Hunter College
Research
My preclinical research delves into the dynamic interplay between neuroimmune regulation and pain sensitivity, with a spotlight on the kynurenine pathway—a key biomarker of inflammation. Leveraging cutting-edge Positron Emission Tomography (PET) imaging, I aim to explore longitudinal disruptions in the KP across preclinical and clinical settings, unveiling critical neuroimmune changes triggered by traumatic brain injury. This innovative approach not only reveals translational biomarkers but also uncovers therapeutic targets to address neuroimmune dysregulation, paving the way for transformative advances in pain management and anesthesia care.
Research Key Collaborators
Primary Research Advisor: Dr. Alana Conti, PhD
Publications
1. Nahmoud I., Woodcock E., Conti A.C. The Kynurenine Pathway: A New Frontier in Understanding Pain Pathogenesis Following Traumatic Brain Injury. (in submission)
2. Bosse K.E., Nahmoud I., Lloyd S.C., Min W., Conti A.C. Post-injury exposure to morphine leads to prolonged pain and neuroinflammatory response to traumatic brain injury. (in submission)
3. Stujenske, J.M., O'Neill P.K., Nahmoud I, Goldberg S., Diaz L., Labkovich M., Hardin W., Bolkan S.S., Reardon T.R., Spellman T.J., Salzman C.D., Gordon J.A., Likhtik E. Prelimbic cortex drives discrimination of non-aversion via amygdalasomatostatin interneurons. Neuron. July 20, 2022. DOI: 10.1016/j.neuron.2022.03.020
4. Nahmoud I., Vasquez J., Cho H., Yusufova L., Talbot S., Casaccia P., Liu J., Likhtik E. Safety training improves subsequent exploration and discrimination learning. Beh. Brain Res. October 12, 2020. DOI: 10.1016/j.bbr.2020.112907