Brain Development and Aging and Related Disorders
Scott Bowen, Ph.D. | Psychology, Obstetrics and Gynecology |
Jessica S. Damoiseaux, Ph.D. | Psychology, Institute of Gerontology |
Vaibhav Diwadkar, Ph.D. | Psychiatry & Behavioral Neurosciences |
Alexander Gow, Ph.D. | Center for Molecular Medicine and Genetics |
E. Mark Haacke, Ph.D. | Biomedical Engineering, Radiology |
Joseph L. Jacobson, Ph.D. | Psychiatry & Behavioral Neurosciences |
Sandra W. Jacobson, Ph.D. | Psychiatry & Behavioral Neurosciences |
Csaba Juhasz, M.D., Ph.D. | Pediatrics, Neurology |
Noa Ofen, Ph.D. | Institute of Gerontology, Pediatrics |
Naftali Raz, Ph.D. | Institute of Gerontology, Psychology |
Jeffrey A. Stanley, Ph.D. | Psychiatry & Behavioral Neurosciences |
Moriah Thomason, Ph.D. | Pediatrics |
John Woodard, Ph.D. | Psychology |
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| Scott Bowen, Ph.D. Psychology, Obstetrics and Gynecology | |
Research Interest
| research focuses on behavioral pharmacology, behavioral toxicology, and neurobehavioral teratology, also to understand why volatile organic solvents, such as toluene and nitrous oxide, are abused.
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Disease/Disorder
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Species
| Rats and mice. | |
Methods
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Key Collaborators
| John Hannigan
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Publications
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| Jessica S. Damoiseaux, Ph.D. Psychology, Institute of Gerontology | |
Research Interest
| Changes in functional and structural brain connectivity in normal and abnormal aging, with a specific focus on the early detection of Alzheimer's disease.
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Disease/Disorder
| Healthy aging and Alzheimer's disease.
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Species
| Human | |
Methods
| functional MRI; diffusion MRI; neuropsychological assessment.
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Key Collaborators
| Serge Rombouts and Jeroen van der Grond, Leiden Institute for Brain and Cognition, the Netherlands.
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Publications
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| Vaibhav A. Diwadkar, Ph.D. Psychiatry & Behavioral Neurosciences, Psychology | |
Research Interest
| Using imaging to study the functional organization of cortico-striatal and cortico-limbic networks in normal development and to understand dysfunction in these circuits in vulnerable and disordered adolescent populations.
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Disease/Disorder
| Schizophrenia and mood disorders.
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Species
| Human | |
Methods
| fMRI and neuropsychology tests.
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Key Collaborators
| Jeffrey Stanley, Nash Boutros, Bob Freedman, David Rosenberg, Otto Muzik, Harry Chugani, Diane Chugani, Joseph Jacobson, Sandra Jacobson
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Publications
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| Alexander Gow, Ph.D. Center for Molecular Medicine and Genetics, Pediatrics, Neurology | |
Research Interest
| White matter disease and relevance to cognitive deficits.
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Disease/Disorder
| Depression, multiple sclerosis, Pelizaeus-Merzbacher, Auditory Processing Disorder.
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Species
| Mouse and Human | |
Methods
| Knockout and transgenic mice, confocal and electron microscopy, psychoacoustics, behavior, MRI ad MRS, biochemistry, microarrays, computational modeling, drug testing to ameliorate neurodegeneration.
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Key Collaborators
| Robert Skoff, Anatomy and Cell Biology (WSU); Zhengqing Hu, Otolaryngology (WSU); Paula Dore-Duffy, Neurology (WSU); Jeff Stanley, Psychiatry (WSU); Shane Perrine, Psychiatry (WSU); Matthew Galloway, Psychiatry (WSU); Mark Cheng, Electrical Engineering (WSU)
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| Joseph L. Jacobson, Ph.D. Psychiatry & Behavioral Neurosciences | |
Research Interest
| Effects of prenatal exposure to alcohol and environmental contaminants (PCBs, mercury, lead) on infant and child development; research methods; study design.
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Disease/Disorder
| Fetal alcohol syndrome, fetal alcohol spectrum disorder, ADHD and alcohol abuse and dependence.
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Species
| Human. | |
Methods
| Neuropsychological assessment, structural MRI, functional MRI and diffusion tensor imaging
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Key Collaborators
| Sandra W. Jacobson (all studies), Christopher Molteno and Ernesta Meintjes (Cape Town neuroimaging and neurobehavioral studies), Gina Muckle (Inuit studies)
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Publications
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| Sandra W. Jacobson, Ph.D. Psychiatry and Behavioral Neurosciences | |
Research Interest
| Studying the effects of prenatal exposure to alcohol, cocaine, smoking and environmental contaminants (PCBs, mercury, lead) on infant and child development, using state-of-the-art neurobehavioral and neuroimaging outcome measures.
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Disease/Disorder
| Fetal alcohol syndrome (FAS), fetal alcohol spectrum disorder (FASD), attention deficit hyperactivity disorder (ADHD), alcohol abuse and dependence in pregnant women and adolescents.
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Species
| human | |
Methods
| Eyeblink conditioning, fMRI, sMRI, DTI, infant and child neuropsychological assessment (standardized and nonstandardized tests) and alcohol and drug ascertainment and dependence.
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Key Collaborators
| Joseph L. Jacobson (all studies), Mark Stanton (EBC), Christopher Molteno and Ernesta Meintjes (Cape Town fMRI and neurobehavioral studies), Gina Muckle (Inuit studies), Cynthia Bearer (meconium), Tim Oberlander and Joanne Weinberg (cortisol and pain reactivity), Charles Nelson (ERP)
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| Csaba Juhasz, M.D., Ph.D. Pediatrics, Neurology | |
Research Interest
| Functional and structural neuroimaging of epilepsy, brain tumors and developmental brain disorders with a particular interest in the pathophysiology and progression of Sturge-Weber Syndrome.
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Disease/Disorder
| Epilepsy, brain tumors, sturge-weber syndrome and developmental brain disorders
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Species
| Human. | |
Methods
| PET imaging and EEG.
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Key Collaborators
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Publications
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| E. Mark Haacke, Ph.D. Biomedical Engineering, Radiology | |
Research Interest
| We are interesting in a wide variety of neuroimaging applications related to neurovascular diseases from multiple sclerosis to dementia.
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Disease/Disorder
| Stroke, trauma, cancer, multiple sclerosis and aging.
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Species
| Human, rats and mice. | |
Methods
| MRI
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Key Collaborators
| Jiani Hu, Norman Cheng, Zhifeng Kou, Albert King, Randy Benson and James Garbern
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Publications
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| Noa Ofen, Ph.D. Institute of Gerontology, Pediatrics | |
Research Interest
| The typical and atypical development of memory systems in the human brain. Functional and structural brain development. Relationship between variation in cognitive and brain development and genetic polymorphism.
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Disease/Disorder
| Developmental disorders, prematurity and schizophrenia
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Species
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Human | |
Methods
| MRI, fMRI, DTI, Cognitive assessment, Genetics.
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Key Collaborators
| Viabhav Diwadkar, Jeffrey Stanley, Naftali Raz, Joe Jacobson, Sandra Jacobson, Sarah Raz, Moriah Thomason
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Publications
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| Naftali Raz, Ph.D. Institute of Gerontology, Psychology | |
Research Interest
| Differential brain aging, its modification by genetic and pathophysiological factors, and its cognitive consequences.
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Disease/Disorder
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Species
| Human | |
Methods
| MRI and cognitive psychology.
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Key Collaborators
| E. Mark Haacke (WSU), Ulman Lindenberger (Max Planck Institute for Human Development, Berlin), Paolo Ghisletta (University of Geneva, Switzerland).
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Publications
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| Jeffrey A. Stanley, Ph.D. Psychiatry & Behavioral Neurosciences | |
Research Interest
| To gain a greater understanding of neurodevelopmental effects of morphology, function and biochemistry on childhood disorders such as ADHD using different MR methodologies.
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Disease/Disorder
| ADHD, schizophrenia, anxiety and mood disorders.
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Species
| Human (pediatric) | |
Methods
| Different MR methodologies.
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Key Collaborators
| Vaibhav Diwadkar, John Hannigan, Mark Greenwald, Nash Boutros, Brian Martis (U. of Michigan), Jair Soares (U. of Texas at Houston)
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Publications
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| Moriah Thomason, Ph.D. Pediatrics | |
Research Interest
| Impact of the function and maturation of multiple, large-scale brain networks on the individual cognitive and emotional developmental trajectories of children. Relationship between variation in these trajectories and variation in individual brain chemistry and genetic composition. Current projects explore development of fetal neural networks and the impact of neural network development and genetic composition on pediatric anxiety.
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Disease/Disorder
| Developmental psychopathology.
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Species
| Human | |
Methods
| fMRI, DTI, resting-state fMRI, endocrine and genetic techniques
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Key Collaborators
| David Rosenberg, Noa Ofen, Douglas Barnett, Gregory Dyson, Mary Roberts
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