School of Medicine

Wayne State University School of Medicine

Obesity and Diabetes

 

Bruce Berkowitz, Ph.D. Anatomy & Cell Biology, Ophthalmology
James Granneman, Ph.D. Neurology, Center for Molecular Medicine and Genetics
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Bruce Berkowitz, Ph.D.
Professor

Anatomy & Cell Biology, Ophthalmology

Research Interest

Our goal is to prevent vision loss and blindness due to diabetic retinopathy and neurodegenerative disease. We develop and apply functional MRI methods to detect the effectiveness of a treatment earlier in the course of disease than is currently possible.

Disease/Disorder

diabetic retinopathy, retinopathy of prematurity, age-related macular degeneration and retinitis pigmentosa

 

Species

Human, rats and mice.

Methods

Manganese-Enhanced MRI  (MEMRI).

Key Collaborators

Tim Kern (Case Western Reserve University), Paul Tofts (Brighton and Sussex Medical School, England)

Publications

PubMed Search (past 5 years).

Division/Laboratory

Laboratory

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James Granneman, Ph.D.
Professor

Psychiatry & Behavioral Neurosciences, Pathology

Research Interest

Adipose tissue remodeling, molecular mechanisms of lipolysis in fat and muscle,  drug target discovery.

Disease/Disorder

Diabetes and obesity.

Species

Mice.

Methods

Confocal microscopy, live cell protein-protein interaction assays, molecular biology, cell biology and high throughput compound screening

Key Collaborators

HP Moore, Ryan Thummel, Mark Cheng, Guangzhao Mao

Publications

PubMed Search (past 5 years).

Division/Laboratory

Center for Integrative Metabolic and Endocrine Research

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